Signal Psilocybin Helps Most Veterans With PTSD, Small Study Shows

Summary

A small clinical trial conducted by researchers at Ohio State University's College of Social Work, including Alan Davis and Stacey Armstrong, tested a psilocybin-assisted therapy protocol in veterans with treatment-resistant PTSD. The 11-week protocol involved 12 veteran participants who received 8 hours of psychotherapy, followed by two doses of synthetic psilocybin administered two to three weeks apart, followed by 6 to 8 hours of integration therapy. One month after dosing, 9 of the 12 participants no longer met diagnostic criteria for PTSD. Of the remaining three participants, two showed symptom reduction and one showed minimal improvement. The most common side effect reported was mild headache following dosing. The results were published in the journal Communications Medicine.