Trend Antimicrobial resistance as a rapidly growing global threat
Summary
The report defines antimicrobial resistance as microorganisms such as fungi, bacteria, viruses and parasites evolving to withstand treatment, which raises the risk of severe illness and death. Resistance arises naturally, but it has been made worse by careless use of antibiotics and antifungals, inadequate infection prevention and control, and poor water, sanitation and hygiene practices. This has led to more infections, imports of resistant strains, and the spread of drug-resistant strains and genes between people and animals and through the environment. The report regards AMR as a fast-growing global threat not only to public health but also to animal and plant health and food security. It records about 1.3 million deaths linked to bacterial AMR in 2019, twice the toll of malaria, and warns that the economic damage from unchecked resistance could exceed that of the 2008-2009 financial crisis.
Classification
Evidence 1
- HM Government - Cabinet Office and Government Office for Science (Foresight) Chronic Risks Analysis HM Government - Cabinet Office and Government Office for Science (Foresight) no link — bibliographic entry p. 87 2025 accessed 2026-09-29
Observed signals 8
- SignalAMR named a high consequence risk in the 2023 Biological Security Strategy
- SignalBacterial AMR linked to 1.3 million deaths in 2019
- SignalGlobal human antibiotic consumption up 46% from 2000 to 2018
- SignalSecond UK five-year AMR National Action Plan launched in 2024
- SignalSevere antibiotic-resistant infections in England rose 6.6% to nearly 58,000
- SignalUK livestock antimicrobial use down 59% since 2014
- SignalUnchecked AMR could cost 100 trillion dollars by 2050
- SignalWorldwide livestock antimicrobial use up an estimated 58% over 2010 to 2020
Part of issues 4
- IssueAgricultural antifungal use and warming spreading fungal infections1 trends · 0 signals
- IssueGlobal antimicrobial use stemmed as in the UK1 trends · 0 signals
- IssueMultidrug-resistant microbes making routine surgery dangerous1 trends · 0 signals
- IssueUntreatable livestock diseases hitting farming and aquaculture1 trends · 0 signals
Relation types: constitutes · supports
Public id: fm-95f44d6f414f
